hlaR: Tools for HLA Data

A streamlined tool for eplet analysis of donor and recipient HLA (human leukocyte antigen) mismatch. Messy, low-resolution HLA typing data is cleaned, and imputed to high-resolution using the NMDP (National Marrow Donor Program) haplotype reference database <https://haplostats.org/haplostats>. High resolution data is analyzed for overall or single antigen eplet mismatch using a reference table (currently supporting 'HLAMatchMaker' <http://www.epitopes.net> versions 2 and 3). Data can enter or exit the workflow at different points depending on the user's aims and initial data quality.

Version: 0.1.1
Depends: R (≥ 3.5.0)
Imports: devtools, usethis, tidyverse, dplyr, reshape2, schoolmath, tibble, stringr, purrr, tidyr, utils, readr, here, readxlsb
Suggests: knitr, rmarkdown
Published: 2021-09-27
Author: Joan Zhang [aut, cre], Aileen Johnson [aut], Christian P Larsen [cph, aut]
Maintainer: Joan Zhang <joan.zhang at emory.edu>
License: MIT + file LICENSE
NeedsCompilation: no
CRAN checks: hlaR results

Downloads:

Reference manual: hlaR.pdf
Vignettes: Imputation
Eplet Mismatch
Package source: hlaR_0.1.1.tar.gz
Windows binaries: r-devel: hlaR_0.1.1.zip, r-release: hlaR_0.1.1.zip, r-oldrel: hlaR_0.1.1.zip
macOS binaries: r-release (arm64): hlaR_0.1.1.tgz, r-release (x86_64): hlaR_0.1.1.tgz, r-oldrel: hlaR_0.1.1.tgz
Old sources: hlaR archive

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