nlmixr2: Nonlinear Mixed Effects Models in Population PK/PD

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Version: 2.0.6
Depends: nlmixr2data
Imports: nlmixr2est, nlmixr2extra, rxode2, nlmixr2plot, magrittr
Suggests: rmarkdown, knitr, devtools, withr, ggplot2, testthat
Published: 2022-05-24
Author: Matthew Fidler ORCID iD [aut, cre], Yuan Xiong [ctb], Rik Schoemaker ORCID iD [ctb], Justin Wilkins ORCID iD [ctb], Wenping Wang [aut], Mirjam Trame [ctb], Huijuan Xu [ctb], John Harrold [ctb], Bill Denney ORCID iD [ctb], Theodoros Papathanasiou [ctb], Teun Post [ctb], Richard Hooijmaijers [ctb]
Maintainer: Matthew Fidler <matthew.fidler at gmail.com>
BugReports: https://github.com/nlmixr2/nlmixr2/issues/
License: GPL (≥ 3)
URL: https://nlmixr2.github.io/nlmixr2/, https://github.com/nlmixr2/nlmixr2/
NeedsCompilation: no
Materials: README NEWS
CRAN checks: nlmixr2 results

Documentation:

Reference manual: nlmixr2.pdf
Vignettes: Running PK models with nlmixr

Downloads:

Package source: nlmixr2_2.0.6.tar.gz
Windows binaries: r-devel: nlmixr2_2.0.6.zip, r-release: nlmixr2_2.0.6.zip, r-oldrel: nlmixr2_2.0.6.zip
macOS binaries: r-release (arm64): nlmixr2_2.0.6.tgz, r-oldrel (arm64): nlmixr2_2.0.6.tgz, r-release (x86_64): nlmixr2_2.0.6.tgz, r-oldrel (x86_64): nlmixr2_2.0.6.tgz

Reverse dependencies:

Reverse suggests: ggPMX, xpose.nlmixr2

Linking:

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